Protein hydration in aqueous solution pdf

Molecular dynamics simulation of solvated azurin: correlation between surface solvent accessibility and water residence times. Residence times of water molecules in the hydration sites of myoglobin. Water rotational relaxation and diffusion in hydrated lysozyme. J Am Chem Soc. Is the first hydration shell of lysozyme of higher density than bulk water? Internal water molecules and H-bonding in biological macromolecules: a review of structural features with functional implications.

Water dynamics in the large cavity of three lipid-binding proteins monitored by 17 O magnetic relaxation dispersion. Dynamics of protein and peptide hydration. Protein hydration and unfolding--insights from experimental partial specific volumes and unfolded protein models.

Fold Des. Large-scale networks of hydration water molecules around bovine beta-trypsin revealed by cryogenic X-ray crystal structure analysis. Dielectric relaxation and solvation dynamics of water in complex chemical and biological systems. Chem Rev. Acuracy of refined protein structures. Comparison of four independently refined models of human interleukin 1beta.

Protein hydration in aqueous solution. J Biomol NMR. Dynamics of water in biological recognition. Biological water at the protein surface: dynamical solvation probed directly with femtosecond resolution. Protein-water interactions determined by dielectric methods. Annu Rev Phys Chem. Carboxypeptidase A: a protein and an enzyme. Protein hydration and function. Contribution of solvent water to the solution X-ray scattering profile of proteins. Hydrodynamics and protein hydration. Arch Biochem Biophys.

Solvent saturation and chemical exchange in superoxide dismutase. FEBS Lett. Protein hydration in solution: experimental observation by x-ray and neutron scattering. Sequential resonance assignments as a basis for the determination of a three-dimensional structure of protein E-L30 of Escherichia coli. Frictional models for stochastic simulations of proteins. Buried waters and internal cavities in monomeric proteins.

Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II. Structure of form III crystals of bovine pancreatic trypsin inhibitor. Find more information on the Altmetric Attention Score and how the score is calculated. Cite this: J. Article Views Altmetric -. Citations Note: In lieu of an abstract, this is the article's first page. Cited By. This article is cited by publications.

Yusuke Okuno, Attila Szabo, G. Marius Clore. Journal of the American Chemical Society , 18 , Journal of Chemical Theory and Computation , 14 2 , The Journal of Physical Chemistry Letters , 8 14 , The Journal of Physical Chemistry B , 27 , Chemical Reviews , 9 , The Journal of Physical Chemistry B , 34 , Dubin , and David A. Nonfreezing Water Structuration in Heteroprotein Coacervates. Langmuir , 31 31 , Ono , Tsutomu Terauchi , and Masatsune Kainosho. Journal of the American Chemical Society , 43 , The Journal of Physical Chemistry B , 49 , The Journal of Physical Chemistry B , 46 , Journal of the American Chemical Society , 17 , Journal of the American Chemical Society , 51 , Journal of the American Chemical Society , 38 , Gross, and, Bo Chen.

Macromolecules , 38 26 , Macromolecules , 36 18 , The Journal of Physical Chemistry B , 50 , Ratner, and, Martin F. One Water Molecule Stiffens a Protein. Journal of the American Chemical Society , 12 , Hoaglund-Hyzer,, Anne E. Counterman, and, David E. Anhydrous Protein Ions. Chemical Reviews , 99 10 , Hudgins, and, Martin F. Journal of the American Chemical Society , 40 , The Journal of Physical Chemistry , 17 , Accounts of Chemical Research , 28 4 , Wang , Hao Ren , Claude B.

Klee , and Ad Bax. Proton, carbon, nitrogen nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B. Biochemistry , 33 12 , Hoitink , Paul C. Driscoll , H. Allen O. Hill , and Gerard W. Garrett , Carl J. March , Eric A. Frieden , Angela M. Gronenborn , and G. The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy.

Biochemistry , 32 26 , Designed replacement of an internal hydration water molecule in BPTI: structural and functional implications of a Gly-to-Ser mutation. Biochemistry , 32 17 , Biochemistry , 32 14 , Canters , Sybren S. Wijmenga , Arjen Lommen , Cees W.

Complete sequential proton and nitrogen nuclear magnetic resonance assignments and solution secondary structure of the blue copper protein azurin from Pseudomonas aeruginosa.

Biochemistry , 31 42 , Bushweller and Paul A. Investigation of an octapeptide inhibitor of Escherichia coli ribonucleotide reductase by transferred nuclear Overhauser effect spectroscopy. Biochemistry , 30 33 , Proceedings of the National Academy of Sciences , 14 , e Short residence times prevail for all surface hydration sites, independent of whether or not they are occupied by well ordered, X-ray observable water in the protein single crystals.

Abstract Proton nuclear magnetic resonance was used to study individual molecules of hydration water bound to the protein basic pancreatic trypsin inhibitor BPTI and to the nonapeptide oxytocin in aqueous solution.

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